Truth of Floating Carotid Plaques
Wei Liu1, Shuo Lu1, Yibo Feng1
1Department of Neurology, China-Japan Friendship Hospital, Beijing, China.
Frontiers in Neurology
|January 10, 2018
Summary
Floating carotid plaque, a high-risk factor for stroke, presents unique histopathology. This case reveals mobile substances are plaque contents, not thrombus, prompting new treatment investigations.
Area of Science:
- Vascular Surgery
- Neurology
- Pathology
Background:
- Floating carotid plaque is an uncommon finding detected via duplex ultrasonography.
- It is recognized as a significant risk factor for embolic cerebrovascular disease.
Observation:
- Histopathological features of floating carotid plaques can vary significantly.
- This case details a floating plaque at the edge of atherosclerotic plaque in the common carotid artery.
Findings:
- Carotid endarterectomy revealed mobile substances were plaque contents protruding after fibrous cap rupture, distinct from mural thrombus.
- This differs from typical ulcer plaque, where mobile substances are usually thrombotic.
Implications:
- Understanding these pathological differences is crucial for investigating the pathogenesis of ischemic cerebrovascular disease caused by floating carotid plaque.
- This case may inform novel treatment strategies for this condition.
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