Related Experiment Video
Updated: Feb 15, 2026

Glioblastoma Relapse Post-Resection Model for Therapeutic Hydrogel Investigations
Published on: February 24, 2023
Degree of Resection and Ki-67 Labeling Index for Recurring Meningiomas
Richard Menger1, David E Connor1, Alvin Y Chan2
1Department of Neurosurgery, LSU Health Sciences Center Shreveport.
Abstract:
Objective Meningioma recurrence after resection is likely influenced by multiple surgical and histologic factors. In this study, the degree of resection and tumor immunoreactivity to MIB-1 (i.e., Ki-67 labeling index (LI)) are described in recurrent and non-recurrent meningioma cases. Methods Data regarding tumor location, the degree of resection, histologic features, and the degree of Ki-67 positivity were collected for 32 patients treated between September 2008 and July 2009. Follow-up for recurrence was assessed through five years. Results A total of 32 patients (13 males; 19 females) underwent resection. The mean age was 53.3 years. Gross total resection (GTR) occurred in 25 (78.1%) cases. Near-total resection (NTR) occurred in five (15.6%) cases. Subtotal resection (STR) occurred in two (6.2%) cases. The overall mean Ki-67 LI score was 9.75% (ranging between 1% to 48%). The mean Ki-67 LI for GTR, NTR, and STR cases were 8.0%, 10.2%, and 29.5% respectively. Tumor recurrence occurred in five (15.6%) patients. The mean Ki-67 LI for recurrence lesions was 22.2%. Conclusion We present our descriptive data for Ki-67 LI for initial tumors and recurrence. The risk of recurrence following resection of meningiomas may be associated with the degree of Ki-67 positivity.
Related Concept Videos
One-Degree-of-Freedom System
A one-degree-of-freedom system is defined by an independent variable that determines its state and behavior. One example of a one-degree-of-freedom system is a simple harmonic oscillator, such as a...
Degrees of Freedom
For example, suppose there are three unknown numbers whose mean is 10; although we can freely assign values to the first and second numbers, the value of the last number can not be arbitrarily assigned.
Degrees of Freedom
For example, suppose there are three unknown numbers whose mean is 10; although we can freely assign values to the first and second numbers, the value of the last number can not be arbitrarily...
Degree of Unsaturation
The degree of unsaturation for hydrocarbons is U = (2C + 2 − H) / 2, where C is the number of carbon atoms and H is the number of hydrogen atoms.
Radian and Degree Measure
Degree of Curvature and Radius of Curvature

