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Updated: Feb 15, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Alfieri stitch for temporary severe functional mitral regurgitation after aortic valve replacement
Yoshihisa Morimoto1, Takaki Sugimoto2
1Department of Cardiovascular Surgery, Ako City Hospital, 1090 Nakahiro, Ako, Hyogo, 678-0232, Japan. yoshimor@gmail.com.
Aortic valve replacement in frail patients can cause hemodynamic instability due to functional mitral regurgitation. An Alfieri stitch effectively treated this, enabling successful cardiopulmonary bypass weaning.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery
- Interventional Cardiology
Background:
- Functional mitral regurgitation (FMR) complicates aortic valve replacement (AVR), particularly in frail patients.
- The management of FMR in elderly, frail patients undergoing AVR remains challenging.
- Left ventricular dilatation can exacerbate FMR, leading to hemodynamic instability.
Purpose of the Study:
- To evaluate the efficacy of a minimally invasive technique for managing FMR in a frail patient undergoing AVR.
- To assess the impact of addressing FMR on hemodynamic stability and cardiopulmonary bypass weaning.
Main Methods:
- A case report of an 82-year-old frail female with severe aortic regurgitation and moderate FMR (NYHA class III).
- Aortic valve replacement was performed without initial mitral valve intervention due to patient frailty.
- A central Alfieri edge-to-edge stitch was employed to correct FMR after AVR when hemodynamic instability occurred.
Main Results:
- The patient experienced hemodynamic instability and difficulty weaning from cardiopulmonary bypass due to severe FMR and left ventricular dilatation post-AVR.
- Placement of a central Alfieri edge-to-edge stitch successfully eliminated mitral regurgitation.
- Successful separation from cardiopulmonary bypass was achieved after the mitral valve intervention.
Conclusions:
- In frail patients undergoing AVR, FMR can lead to significant complications.
- The Alfieri edge-to-edge technique is a viable option for treating FMR in selected high-risk patients.
- This approach can improve hemodynamic stability and facilitate weaning from cardiopulmonary bypass.
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