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Updated: Feb 15, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Mesenteric Panniculitis-First Case Series After Bariatric Surgery
Amrit Manik Nasta1, Dipti Patel2, Om Shrivastav2
1Wockhardt Hospitals, Mumbai Central, Mumbai, India. amritnasta@hotmail.com.
Abstract:
Mesenteric panniculitis is an uncommon pathology, of poorly understood etiology, characterized by progressive inflammation and fibrosis of the small bowel mesentery. This disease has been reported usually after other abdominal surgeries. We present two cases of young male patients who underwent laparoscopic sleeve gastrectomy and developed abdominal symptoms within 45-60 days of surgery. Both were investigated for known post-bariatric complications. While first patient presented (5 months later) at an irreversible stage and died within 8-9 months of primary surgery, in second patient, the disease process could be reversed through early intervention, diagnosis, treatment, and compliance. Mesenteric panniculitis is a rapidly progressive entity, which can be adequately treated by early identification and long-term immune-suppressive therapy.
Insights
Mesenteric panniculitis, a rare inflammatory condition, can occur after bariatric surgery. Early diagnosis and treatment are crucial for managing this progressive disease.
Area of Science:
- Gastroenterology and Surgical Pathology
Background:
- Mesenteric panniculitis is a rare condition involving inflammation and fibrosis of the small bowel mesentery.
- Its etiology is poorly understood, and it is often associated with prior abdominal surgeries.
Observation:
- Two young male patients developed abdominal symptoms 45-60 days post-laparoscopic sleeve gastrectomy.
- Initial investigations focused on common post-bariatric complications.
Findings:
- One patient progressed to an irreversible stage, succumbing to the disease within 8-9 months.
- The second patient achieved disease reversal through prompt diagnosis, intervention, and adherence to long-term immunosuppressive therapy.
Implications:
- Mesenteric panniculitis is a rapidly progressive condition requiring timely identification.
- Early intervention with immunosuppressive therapy can lead to favorable outcomes and disease reversal.
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