Cardiovascular complications after non-cardiac surgery
D Sellers1, C Srinivas1, G Djaiani1
1Toronto General Hospital, University of Toronto, Toronto, Canada.
Insights
Cardiac complications like myocardial injury after non-cardiac surgery are common and linked to poor outcomes. This review covers causes, prevention, and treatment strategies for peri-operative cardiac events, including arrhythmias and heart failure.
Area of Science:
- Cardiology
- Anesthesiology
- Peri-operative Medicine
Background:
- Cardiac complications are frequent following non-cardiac surgery.
- Myocardial injury after non-cardiac surgery (MINS), indicated by troponin rise, is increasingly recognized and associated with poor prognosis.
- Postoperative arrhythmias and heart failure, including diastolic dysfunction, are significant concerns.
Purpose of the Study:
- To review the epidemiology, causation, prevention, and treatment of cardiac complications after non-cardiac surgery.
- To examine the impact of pre-operative diastolic dysfunction on postoperative outcomes.
- To guide fluid management for anesthesiologists based on current evidence.
Main Methods:
- Review of international guidelines and landmark studies on peri-operative cardiac events.
- Analysis of evidence concerning myocardial injury after non-cardiac surgery (MINS).
- Examination of data on postoperative arrhythmias (atrial fibrillation, QT prolongation) and heart failure (systolic and diastolic).
Main Results:
- Peri-operative myocardial infarction affects 3% of major surgery patients.
- Myocardial injury after non-cardiac surgery (MINS) has a poor prognosis.
- Diastolic dysfunction is increasingly recognized as a cause of postoperative heart failure.
Conclusions:
- Understanding and managing peri-operative cardiac injury, including MINS, is crucial.
- Evidence-based strategies for prevention and treatment of cardiac complications should be implemented.
- Awareness of diastolic dysfunction is vital for appropriate fluid management in non-cardiac surgery.
Abstract:
Cardiac complications are common after non-cardiac surgery. Peri-operative myocardial infarction occurs in 3% of patients undergoing major surgery. Recently, however, our understanding of the epidemiology of these cardiac events has broadened to include myocardial injury after non-cardiac surgery, diagnosed by an asymptomatic troponin rise, which also carries a poor prognosis. We review the causation of myocardial injury after non-cardiac surgery, with potential for prevention and treatment, based on currently available international guidelines and landmark studies. Postoperative arrhythmias are also a frequent cause of morbidity, with atrial fibrillation and QT-prolongation having specific relevance to the peri-operative period. Postoperative systolic heart failure is rare outside of myocardial infarction or cardiac surgery, but the impact of pre-operative diastolic dysfunction and its ability to cause postoperative heart failure is increasingly recognised. The latest evidence regarding diastolic dysfunction and the impact on non-cardiac surgery are examined to help guide fluid management for the non-cardiac anaesthetist.
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