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Updated: Feb 15, 2026
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Transplantation of Olfactory Ensheathing Cells to Evaluate Functional Recovery after Peripheral Nerve Injury
Published on: February 23, 2014
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Peripheral nerve injury arising in anaesthesia practice.
D W Hewson1, N M Bedforth1, J G Hardman2
1Department of Anaesthesia, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Anaesthesia
|January 10, 2018
Summary
Peripheral nerve injury during anesthesia can be prevented by understanding risk factors and employing evidence-based management strategies. This includes careful patient positioning and optimized nerve blockade techniques to minimize nerve damage.
Area of Science:
- Anesthesiology
- Neurology
- Surgical Safety
Background:
- Peripheral nerve injury (PNI) is a recognized complication in anaesthetic practice.
- Factors influencing nerve susceptibility and injury patterns require detailed understanding.
Purpose of the Study:
- To elucidate the pathophysiology of PNI in anaesthesia.
- To outline evidence-based management for suspected PNI.
- To discuss injury patterns and preventative strategies for nerve blockade.
Main Methods:
- Review of pathophysiology of PNI.
- Analysis of intra-operative positioning and peripheral nerve blockade risks.
- Evidence synthesis on PNI reduction strategies during nerve blockade.
Main Results:
- Identified risk factors increasing nerve susceptibility.
- Described practical management approaches for PNI.
- Detailed major nerve injury patterns and preventative measures.
Conclusions:
- Understanding PNI pathophysiology is crucial for anaesthetic practice.
- Evidence-based strategies, including optimized nerve blockade, can reduce PNI incidence.
- Proactive management and technique refinement are key to patient safety.
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