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Peri-operative neurological complications
R Hood1, A Budd1, F A Sorond2
1Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Insights
Brain injury after cardiac surgery is a growing concern, especially in elderly patients. This review covers causes, risks, and prevention strategies for stroke, cognitive dysfunction, and delirium to protect the brain.
Area of Science:
- Neurology
- Cardiology
- Geriatrics
Background:
- Cardiac surgery poses significant risks for brain injury, impacting patient morbidity and mortality.
- The increasing elderly population undergoing cardiac procedures heightens the frequency of these neurological complications.
Purpose of the Study:
- To review the causes and risk factors associated with peri-operative stroke, postoperative cognitive dysfunction, and postoperative delirium.
- To discuss prevention strategies, including brain protection, embolism avoidance, and management of cerebral hypoperfusion.
Main Methods:
- Literature review of studies on brain injury following cardiac surgery.
- Analysis of risk factors, aetiology, and preventative measures for neurological complications.
Main Results:
- Identified key risk factors and aetiologies for peri-operative neurological deficits.
- Outlined various brain protection strategies and methods to prevent cerebral embolism and hypoperfusion.
Conclusions:
- Advanced age is a critical risk factor for brain injury after cardiac surgery.
- Proactive prevention strategies are essential to mitigate neurological complications and improve patient outcomes.
Abstract:
Brain injury from cardiac surgery is an important source of patient morbidity and mortality. The relationship between risk of brain injury and advanced age portends a rising frequency of these complications due to an increasing proportion of elderly patients undergoing cardiac surgery. This review will explore the aetiology and risk factors for peri-operative stroke, postoperative cognitive dysfunction and postoperative delirium. The prevention of each of these conditions will also be discussed, with a focus on brain protection strategies and the avoidance of cerebral embolism and hypoperfusion.
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