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Updated: Feb 15, 2026

Preparation of Peripheral Nerve Stimulation Electrodes for Chronic Implantation in Rats
Published on: July 14, 2020
Peripheral Nerve Stimulation for Chronic Shoulder Pain: A Proof of Concept Anatomy Study
1University of Toronto, Toronto, ON, Canada.
Objectives:
Although spinal cord and dorsal root ganglia stimulation may be effective for managing regional pain syndromes, a more targeted approach is perhaps more appealing for discrete anatomical structures. Chronic shoulder pain is a common musculoskeletal problem with significant socioeconomic impact. A peripheral nerve stimulation of the axillary and suprascapular nerves may prove to be effective as a long-term solution for this indication. In anticipation of the future experimental research and clinical utilization, a sound methodology for the lead placement was developed, and its feasibility is tested in a cadaveric study.
Materials And Methods:
Normal anatomy was corroborated with ultrasound scans of live models and cadaver specimens. A step-by-step ultrasound-guided implantation technique was designed. The procedure was completed targeting both the axillary and suprascapular nerves. The accuracy of the lead placement was confirmed by dissections.
Results:
The implanted devices were found adjacent to the target nerves within 0.5-1 cm distance.
Conclusions:
The anatomical dissections confirmed the accuracy of ultrasound-guided placement of the lead. The described method is based on normal anatomy and appeared to be reproducible by following the outlined procedural steps.
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