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Advanced Inorganic Nanosystems for Skin Drug Delivery
E Carazo1, A Borrego-Sánchez1,2, F García-Villén1
1Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, University of Granada, Campus of Cartuja, 18071 s/n, Granada, Spain.
Chemical Record (New York, N.Y.)
|January 10, 2018
Summary
Inorganic nanoparticles offer a promising approach for enhanced skin drug delivery, overcoming the skin barrier to improve therapeutic effects and reduce side effects. This review explores their potential in advanced transdermal and topical applications.
Area of Science:
- Biomedical Engineering
- Materials Science
- Nanotechnology
Background:
- Transdermal drug delivery is a viable alternative to oral administration for localized or systemic treatment.
- The skin's complex structure presents a significant barrier to effective drug penetration.
- Developing advanced drug delivery systems is crucial for enhancing therapeutic efficacy and minimizing adverse effects.
Purpose of the Study:
- To provide a comprehensive overview of current trends in skin drug delivery.
- To highlight the potential of inorganic nanoparticles in overcoming skin barriers.
- To focus on inorganic-based nanosystems as an attractive alternative for drug delivery.
Main Methods:
- Review of existing literature on skin drug delivery systems.
- Analysis of the properties of inorganic nanoparticles for drug delivery applications.
- Focus on nanosystems designed to enhance skin penetration.
Main Results:
- Inorganic nanoparticles possess favorable properties like biocompatibility, biodegradability, and cost-effectiveness.
- These nanoparticles show significant potential for developing effective skin drug delivery systems.
- Nanosystems offer a promising strategy to improve drug permeation through the skin.
Conclusions:
- Inorganic nanoparticles are well-suited for advanced skin drug delivery applications.
- Nanosystems represent a key trend in overcoming the skin barrier for enhanced drug delivery.
- Further research into inorganic-based nanosystems can lead to improved therapeutic outcomes.
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