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Updated: Feb 15, 2026

Transthoracic Echocardiography in Mice
Published on: May 28, 2010
Oversensing of transthoracic excitation stimuli in contemporary pacemakers
James D Ryan1, Nathan D Tempel1, Dean D Engle1
1Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Background:
Transthoracic impedance measurements (TIM) is primarily used for minute ventilation rate adaptive sensors in pacemakers. With elevated impedance, the TIM electrical signal itself is oversensed, causing device malfunction.
Objective:
We report an increased incidence of TIM oversensing.
Method:
Retrospective chart review. We review existing records of 18 patients who have demonstrated device malfunction with TIM oversensing.
Results:
We have found a 1.8% incidence of TIM-related oversensing in our patient population of 959 patients with contemporary Boston Scientific (Marlborough, MA, USA) pacemakers and cardiac resynchronization therapy pacemakers. One patient experienced a syncopal episode.
Conclusion:
Oversensing with pacing inhibition is apparent with the potential of adverse effects to patients.
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