Short-term and long-term clinical outcomes of rotational atherectomy in resistant chronic total occlusion
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Published on: May 19, 2023
Wei-Chieh Huang1, Hsin-I Teng2, Wan-Leong Chan3
1Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
Insights
Rotational atherectomy (RA) is safe and effective for treating complex, calcified coronary chronic total occlusions (CTOs). This intervention shows excellent short- and long-term outcomes comparable to cases not requiring RA.
Area of Science:
- Interventional Cardiology
- Cardiovascular Disease Management
Background:
- Percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs) can be challenging, particularly with heavily calcified lesions.
- Rotational atherectomy (RA) is a technique used to address complex lesions during PCI.
Purpose of the Study:
- To assess the clinical outcomes of using rotational atherectomy (RA) in patients undergoing percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs).
- To evaluate the safety and efficacy of RA for resistant CTO lesions, defined by heavy calcification or inability of devices to cross.
Main Methods:
- A study of 285 patients with CTO who underwent successful PCI between January 2011 and September 2014.
- Resistant CTO lesions were identified, and 26 patients were treated with RA.
- Outcomes were compared between the RA group and a non-RA group, with a mean follow-up of 3.4 years.
Main Results:
- RA successfully treated all 26 resistant CTO lesions with a high success rate (96.2%) and no major complications, except for one requiring surgery.
- The RA group had a higher success rate (96.2%) compared to the non-RA group (89.5%, P=0.038).
- Patients in the RA group were older, had higher J-CTO scores, and required longer stents, but demonstrated excellent and comparable 1-year and long-term clinical outcomes.
Conclusions:
- Rotational atherectomy (RA) is a safe and feasible option for treating resistant chronic total occlusions (CTOs) characterized by heavy calcification.
- The short- and long-term clinical outcomes following RA for CTO PCI are excellent and comparable to procedures not requiring RA.
Objectives:
To evaluate the short- and long-term clinical outcomes of RA in CTO coronary intervention.
Background:
The application of rotational atherectomy (RA) may improve the success rate of percutaneous recanalization of chronic total occlusion (CTO) with heavy calcification.
Methods:
From January 2011 to September 2014, we enrolled 285 patients with CTO who underwent successful percutaneous coronary intervention (PCI). Resistant CTO lesions were defined as those with heavy calcifications as well as those that no devices are able to pass after guide wire crossing.
Results:
All patients with resistant CTO lesions (n = 26) were successfully treated by RA without major complications, except 1 patient complicated with coronary perforation and treated by surgery successfully (success rate: RA group vs non-RA group: 96.2%, vs 89.5%, P = 0.038). Compared to the non-RA group, the patients in the RA group were older (P = 0.028), had higher J-CTO scores (P = 0.001), and needed longer stents (P = 0.001). All patients were followed up for a mean period of 3.4 ± 2.3 years, and the 1-year and long-term clinical outcomes of the RA group were excellent and comparable with those not receiving RA in multivariate analysis adjusted for multiple variables.
Conclusion:
The treatment of RA is safe and feasible for resistant CTO lesions with heavy calcification. The short- and long-term clinical outcomes of the treatment of RA were excellent and comparable with those not needing RA for CTO PCI.
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