Blood Lead Levels and Risk Factors for Lead Exposure in a Pediatric Population in Ho Chi Minh City, Vietnam

Deborah Havens1,2, Minh Hong Pham3, Catherine J Karr4

  • 1Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98195, USA. havensde@uw.edu.

Insights

Elevated blood lead levels (BLL) affect 7% of children in Vietnam, with higher risks for those over 12 months and living in specific provinces. This highlights the need for targeted interventions to reduce lead exposure risks.

Area of Science:

  • Environmental Health
  • Pediatric Toxicology
  • Public Health

Background:

  • Lead recycling is a known risk factor for elevated blood lead levels (BLL) in Southeast Asia.
  • Limited data exists on BLL prevalence and risk factors in Vietnam's general pediatric population.
  • Understanding these factors is crucial for public health initiatives.

Purpose of the Study:

  • To evaluate the prevalence of elevated BLLs in children in Vietnam.
  • To identify risk factors associated with higher BLLs in this population.

Main Methods:

  • A cross-sectional study involving 311 children from Children's Hospital #2 in Ho Chi Minh City, Vietnam.
  • Capillary blood lead testing was conducted using the LeadCare II system.
  • Statistical analysis identified associations between demographic and geographic factors and BLLs.

Main Results:

  • The mean BLL was 4.97 μg/dL (SD 5.50).
  • 7% of participants exhibited BLLs greater than 10 μg/dL.
  • Living in Bing Duong or Dong Nai provinces and being older than 12 months were significantly associated with higher BLLs.

Conclusions:

  • The prevalence of elevated BLLs in Vietnam is comparable to other Southeast Asian countries.
  • Mean BLLs in Ho Chi Minh City were lower than in areas with lead recycling activities.
  • Further research is needed to refine risk factor identification for effective screening programs in Vietnam.

Related Concept Videos

Phase-lead and Phase-lag Controllers01:22

Phase-lead and Phase-lag Controllers

Understanding the working function of different types of controllers can be illustrated with practical analogies, such as adjusting a stereo's volume equalizer. Cranking up the bass involves a phase-lead controller, which functions as a high-pass filter, while increasing the treble uses a phase-lag controller, which acts as a low-pass filter. PD controllers, similar to high-pass filters, enhance the system's response to high-frequency components. PI controllers, akin to low-pass...
585
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.9K
Time and frequency -Domain Interpretation of Phase-lead Control01:24

Time and frequency -Domain Interpretation of Phase-lead Control

Phase-lead controllers are commonly used in various control systems to enhance response speed and stability. Adjusting the brightness on a television screen offers a practical example of phase-lead control. When contrast is enhanced, a phase-lead controller is employed. Mathematically, phase-lead control is identified when the first parameter is smaller than the second.
The design of phase-lead control involves the strategic placement of poles and zeros to balance steady-state error and system...
481
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
18
Conservation of Small Populations02:04

Conservation of Small Populations

Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
17.5K
Chi-square Distribution01:10

Chi-square Distribution

How does one determine if bingo numbers are evenly distributed or if some numbers occurred with a greater frequency? Or if the types of movies people preferred were different across different age groups or if a coffee machine dispensed approximately the same amount of coffee each time. These questions can be addressed by conducting a hypothesis test. One distribution that can be used to find answers to such questions is known as the chi-square distribution. The chi-square distribution has...
7.0K