Related Experiment Video
Updated: Feb 15, 2026

Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications
Published on: September 2, 2025
Optimizing Success and Avoiding Mishaps in the Most Difficult Image-guided Breast Biopsies
Sughra Raza1, Sona A Chikarmane1, Eva C Gombos1
1Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Abstract:
Breast cancer is an increasing challenge in developed and limited resource areas of the world. Early detection of breast cancer offers the best chance for optimal care and best outcomes. A critical step in early detection is to obtain efficient and accurate tissue diagnoses. Although image-guided core needle breast biopsies are usually straightforward for experienced breast imagers, there are some not uncommon scenarios that present particular challenges. In this review article we will discuss these difficult situations and offer our tried and true methods to ensure safe and successful biopsies, while using stereotactic, ultrasound, and MRI guidance.
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