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Updated: Feb 15, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Successful recanalization of long femoro-crural occlusive disease after failed bypass surgery
Grigorios Korosoglou1, Tom Eisele2, Dorothea Raupp3
1Cardiology and Vascular Medicine, GRN Academic Teaching Hospital, Weinheim 69469, Germany. grigorios.korosoglou@grn.de.
Insights
This case study details a successful endovascular treatment for critical limb ischemia using a retrograde approach to cross a stent occlusion. The intervention resolved ischemic pain and healed foot ulcers in a patient with severe comorbidities.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Endovascular Therapy
Background:
- Critical limb ischemia (CLI) requires urgent revascularization, with endovascular procedures being the preferred approach.
- The patient presented with CLI, including ischemic rest pain and ulceration, in the left limb.
- Previous surgical interventions included left femoral popliteal bypass, femoral thromboendarterectomy, and patch angioplasty.
Observation:
- Doppler sonography and MR angiography revealed extensive arterial occlusion in the superficial femoral artery (SFA), popliteal artery, and all three infra-popliteal arteries.
- An initial antegrade endovascular approach failed to cross the occlusion.
- A previously placed stent in the mid-SFA was identified and subsequently targeted for direct puncture.
Findings:
- A retrograde approach via direct SFA stent puncture successfully crossed the occlusions.
- Initial balloon angioplasty of the SFA, popliteal, and posterior tibial arteries yielded suboptimal results.
- A staged endovascular approach with drug-coated balloons and fibular artery recanalization in a second session optimized the treatment and outflow.
Implications:
- Direct retrograde puncture of a stent can be an effective strategy for complex femoropopliteal occlusions.
- A staged endovascular approach may be necessary for optimizing outcomes in CLI patients with severe disease.
- Successful revascularization led to complete resolution of ischemic pain and healing of foot ulceration, improving limb salvage and patient quality of life.
Abstract:
Patients with critical limb ischemia necessitate immediate intervention to restore blood flow to the affected limb. Endovascular procedures are currently preferred for these patients. We describe the case of an 80-year-old female patient who presented to our department with ischemic rest pain and ulceration of the left limb. The patient had history of left femoral popliteal bypass surgery, femoral thromboendarterectomy and patch angioplasty of the same limb 2 years ago. Doppler sonography and magnetic resonance angiography revealed an occlusion of the left superficial femoral artery (SFA) and popliteal artery and of all three infra-popliteal arteries. Due to severe comorbidities, the patient was scheduled for a digital subtraction angiography. An antegrade approach was first attempted, however the occlusion could not be passed. After revision of the angiography acquisition, a stent was identified at the level of the mid SFA, which was subsequently directly punctured, facilitating the retrograde crossing of the occlusion. Thereafter, balloon angioplasty was performed in the SFA, popliteal artery and posterior tibial artery. The result was considered suboptimal, but due to the large amount of contrast agent used, a second angiography was planned in 4 wk. In the second session, drug coated balloons were used to optimize treatment of the SFA, combined with recanalization of the left fibular artery, to optimize outflow. The post-procedural course was uneventful. Ischemic pain resolved completely after the procedure and at 8 wk of follow-up and the foot ulceration completely healed.
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