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[Fatal outcome in a patient coinfected by malaria and HIV]

P Féron1, D Dechamps2, D Konopnicki3

  • 1Service des Urgences, C.H.U. Saint-Pierre, ULB.

Revue Medicale De Bruxelles
|January 11, 2018
PubMed

Insights

Imported malaria, particularly Plasmodium falciparum, poses severe risks for HIV patients. Despite rapid parasite reduction with Artesunate, a fatal cerebral malaria case highlights the critical need for malaria prevention in HIV travelers.

Area of Science:

  • Infectious Diseases
  • Tropical Medicine
  • Immunology

Background:

  • Imported malaria is primarily caused by Plasmodium falciparum.
  • Co-morbidities like HIV increase malaria severity.
  • HIV-malaria co-infection presents unique clinical challenges.

Observation:

  • A case of cerebral malaria in an HIV-positive patient is presented.
  • The patient experienced a fatal outcome despite prompt treatment with Artesunate.
  • Rapid decline in parasitaemia was observed post-treatment.

Findings:

  • Artesunate effectively reduces Plasmodium falciparum parasitaemia.
  • Cerebral malaria in HIV patients can have a lethal evolution.
  • The interplay between HIV and malaria exacerbates disease severity.

Implications:

  • Artesunate plays a crucial role in managing malaria, even in complex cases.
  • Preventive measures are paramount for HIV individuals traveling to malaria-endemic regions.
  • Understanding the HIV-malaria relationship is vital for clinical management and public health strategies.
Keywords:
ArtesunateCo-infectionHuman immunodeficiency virus (HIV)Malaria

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