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Updated: Feb 15, 2026

A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information
Published on: July 1, 2020
Association between Metabolic Syndrome and Job Rank
Ramin Mehrdad1, Gholamreza Pouryaghoub1, Mahboubeh Moradi2
1Center for Research on Occupational Diseases, Tehran University of Medical Sciences, Tehran, Iran.
Background:
The occupation of the people can influence the development of metabolic syndrome.
Objective:
To determine the association between metabolic syndrome and its determinants with the job rank in workers of a large car factory in Iran.
Methods:
3989 male workers at a large car manufacturing company were invited to participate in this cross-sectional study. Demographic and anthropometric data of the participants, including age, height, weight, and abdominal circumference were measured. Blood samples were taken to measure lipid profile and blood glucose level. Metabolic syndrome was diagnosed in each participant based on ATPIII 2001 criteria. The workers were categorized based on their job rank into 3 groups of (1) office workers, (2) workers with physical exertion, and (3) workers with chemical exposure. The study characteristics, particularly the frequency of metabolic syndrome and its determinants were compared among the study groups.
Results:
The prevalence of metabolic syndrome in our study was 7.7% (95% CI 6.9 to 8.5). HDL levels were significantly lower in those who had chemical exposure (p=0.045). Diastolic blood pressure was significantly higher in those who had mechanical exertion (p=0.026). The frequency of metabolic syndrome in the office workers, workers with physical exertion, and workers with chemical exposure was 7.3%, 7.9%, and 7.8%, respectively (p=0.836).
Conclusion:
Seemingly, there is no association between metabolic syndrome and job rank.
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