Related Experiment Video
Updated: Feb 15, 2026

Evaluation of Nanoparticle Uptake in Tumors in Real Time Using Intravital Imaging
Published on: June 21, 2011
Significance of splenic uptake on somatostatin receptor imaging studies
Ismet Sarikaya1, Ali Sarikaya, Naheel Alnafisi
1isarikaya99@yahoo.com.
Abstract:
Spleen shows a high physiological uptake on radionuclide somatostatin receptor (SSTR) imaging studies. Autoradiography and immunohistochemistry studies showed that SSTRs are mainly located in the red pulp of the spleen. In this review article we will summarize the significance of splenic uptake in SSTR imaging studies and will also present high resolution splenic images of Ga-68 DOTANOC PET in which splenic distribution of the radiotracer appears to be correlating with the distribution of red pulp.
Related Concept Videos
Statistical Significance
Receptor-mediated Endocytosis
Significance of Center of Mass
The Significance of Membrane Transport
Transporters facilitate either an active or passive movement of solutes. They can allow a single-molecule transport down its...
Cholesterol: Significance and Regulation
Considering cholesterol and...
Significance Testing: Overview

