Spectrum of Coronary Artery Aneurysms: From the Radiologic Pathology Archives
Jean Jeudy1, Charles S White1, Seth J Kligerman1
1From the Department of Diagnostic Radiology and Nuclear Medicine (J.J., C.S.W., R.H., A.A.F.) and Department of Pathology (A.P.B.), University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201; Department of Radiology, University of California San Diego School of Medicine, San Diego, Calif (S.J.K.); Department of Radiology, Yale University School of Medicine, New Haven, Conn (J.L.K.); Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pa (J.W.S.); Department of Radiology, North Shore University Hospital, Manhasset, NY (A.B.S.); and American Institute for Radiologic Pathology, American College of Radiology, Silver Spring, Md (A.A.F.).
Coronary artery aneurysms (CAAs) have diverse causes, including atherosclerosis and Kawasaki disease, presenting varied symptoms and complications. Diagnosis involves multiple imaging techniques, with management tailored to individual patient needs.
Area of Science:
- Cardiology
- Vascular Medicine
- Diagnostic Imaging
Background:
- Coronary artery aneurysms (CAAs) are increasingly recognized, with diverse etiologies and clinical presentations.
- Pathological classification includes atherosclerotic, inflammatory, and noninflammatory groups, often with overlapping features.
- Atherosclerosis is a primary cause in adults, while Kawasaki disease is predominant in children, frequently leading to multiple CAAs.
Purpose of the Study:
- To provide a comprehensive overview of coronary artery aneurysms.
- To discuss the classification, causes, and clinical manifestations of CAAs.
- To outline diagnostic imaging modalities and management strategies for CAAs.
Main Methods:
- Review of existing medical literature on coronary artery aneurysms.
- Analysis of pathological classifications and etiological factors.
- Summary of current diagnostic and therapeutic approaches.
Main Results:
- CAAs can arise from various clinical scenarios, exhibiting variable symptoms and imaging findings.
- Common causes include atherosclerosis (adults) and Kawasaki disease (children), often resulting in multiple aneurysms.
- Potential complications encompass thrombosis, rupture, myocardial infarction, and cardiac tamponade.
Conclusions:
- Coronary artery aneurysms require a multi-faceted diagnostic approach utilizing various imaging modalities.
- Management strategies are individualized, ranging from surveillance to interventional procedures and surgery.
- Understanding the diverse causes and potential complications is crucial for effective patient care.
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Coronary Artery Disease I: Introduction
Coronary Artery Disease II: Pathophysiology
Coronary Artery Disease V: Interprofessional Care
Coronary Artery Disease III: Clinical Manifestations
Coronary Artery Disease IV: Preventive Measures


