Related Experiment Video
Updated: Feb 15, 2026
05:45
Composition and Distribution Analysis of Bioaerosols Under Different Environmental Conditions
Published on: January 7, 2019
12.3K
Thyroid transcriptome analysis reveals different adaptive responses to cold environmental conditions between two
Shanshan Xie1, Xukai Yang1, Dehe Wang1
1National Engineering Laboratory for Animal Breeding and MOA Key Laboratory of Animal Genetics and Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Plos One
|January 11, 2018
Summary
Bashang Long-tail chickens exhibit superior cold tolerance and adaptability compared to Rhode Island Red chickens, offering valuable insights for improving poultry production and welfare in cold environments.
Area of Science:
- Animal Science
- Genomics
- Physiology
Background:
- Cold tolerance is crucial for chicken production and welfare.
- Thyroid gland function is vital for thermal adaptation but poorly understood in chickens.
- Breed differences in thyroid function and plasticity are key to understanding cold adaptation.
Purpose of the Study:
- To compare the cold tolerance and production performance of Bashang Long-tail (BS) and Rhode Island Red (RIR) chickens.
- To investigate thyroid gland transcriptome profiles and identify molecular mechanisms of cold adaptation.
- To evaluate breed-specific responses to cold environments.
Main Methods:
- Comparative analysis of egg production, body weight, and serum thyroid hormones in BS and RIR chickens under cold and warm conditions.
- RNA sequencing (RNA-Seq) to profile thyroid gland transcriptomes.
- Differential gene expression and splicing event analysis.
Main Results:
- BS chickens showed better cold adaptability, with higher egg production and stable body weight gain in cold environments compared to RIR chickens.
- BS chickens exhibited higher serum thyroid hormone concentrations and distinct thyroid transcriptome profiles related to cell replication and immune response.
- Cold environments reduced transcriptomic differences between breeds, but BS chickens demonstrated greater transcriptional plasticity and adaptive responses.
- Significant differential splicing events were identified, including a shorter isoform of thyroid peroxidase (TPO) in both breeds under cold conditions.
Conclusions:
- The Bashang Long-tail breed is a promising candidate for selection for cold tolerance in chickens.
- Thyroid gland transcriptional plasticity plays a significant role in chicken cold adaptation, with BS chickens showing greater responsiveness.
- Understanding breed-specific transcriptomic and splicing variations can inform strategies for enhancing poultry resilience to cold stress.
Related Concept Videos
02:45Responses to Heat and Cold Stress
14.9K
Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
14.9K
01:21Masonry in Cold and Hot Weather Conditions
353
In cold weather, masonry construction requires specific precautions to ensure mortar does not freeze before curing, as this can significantly weaken its strength and watertightness. Mortar temperature should be maintained between 60°F and 80°F to support proper hydration and curing. Below 40°F, mortar water must be heated, but should not exceed 120°F as high temperatures can reduce mortar's compressive and bond strength.
Other key practices include keeping masonry units...
Other key practices include keeping masonry units...
353
01:59Plant Breeding and Biotechnology
21.9K
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
21.9K
01:23Cells of the Adaptive Immune Response
9.1K
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
9.1K
01:23The Thyroid Gland
7.9K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
7.9K
01:27Cold Weather Concreting
391
When freshly poured concrete is exposed to freezing temperatures before it has set, the water within the concrete can freeze. This expansion disrupts the setting process, delays chemical reactions necessary for hardening, and increases the volume of pores within the hardened concrete, which weakens its overall structure. If the concrete manages to reach an appreciable strength before it freezes, the damage can be somewhat mitigated.
To counteract the negative impacts of cold weather, ensuring...
To counteract the negative impacts of cold weather, ensuring...
391