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Nebulized ketamine to avoid mechanical ventilation in a pediatric patient with severe asthma exacerbation

Abdelghafour Elkoundi1, Aziza Bentalha1, Alae El Koraichi1

  • 1Pediatric Intensive Care Unit, Children Hospital of Rabat, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco.

The American Journal of Emergency Medicine
|January 12, 2018
PubMed

Insights

Nebulized ketamine offers a potential alternative for severe asthma exacerbations in children unresponsive to standard treatments. This approach may help avoid the need for mechanical ventilation in pediatric patients.

Area of Science:

  • Pediatric Pulmonology
  • Emergency Medicine
  • Pharmacology

Background:

  • Asthma remains a significant cause of childhood morbidity and mortality.
  • Severe asthma exacerbations can necessitate mechanical ventilation when standard treatments fail.
  • Identifying alternative therapeutic strategies is crucial for managing refractory pediatric asthma.

Observation:

  • A 26-month-old girl presented with a severe asthma exacerbation.
  • The patient did not respond adequately to conventional asthma therapies.
  • Mechanical ventilation was considered as a potential next step.

Findings:

  • Nebulized ketamine was administered to the pediatric patient.
  • This intervention successfully managed the severe asthma exacerbation.
  • Mechanical ventilation was ultimately avoided.

Implications:

  • Nebulized ketamine may serve as a viable option to prevent mechanical ventilation in children with severe, refractory asthma.
  • This case highlights a potential novel therapeutic approach for severe pediatric asthma exacerbations.
  • Further research into nebulized ketamine for pediatric asthma is warranted.

Keywords:
ChildrenMechanical ventilationNebulized ketamineSevere asthma exacerbation

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