Vaccine-associated paralytic poliomyelitis in a patient with acute lymphocytic leukemia

Reza Taherkhani1, Fatemeh Farshadpour2, Mohammad Reza Ravanbod3

  • 1Persian Gulf Tropical Medicine Research Center, Faculty of Medicine, Bushehr University of Medical Sciences, Moallem Street, Bushehr, Iran.

Journal of Neurovirology
|January 12, 2018
PubMed

Insights

A case of vaccine-associated paralytic poliomyelitis (VAPP) occurred in an immunocompromised patient. Early diagnosis of vaccine-related poliovirus (VRPV) infection is crucial for patient management and preventing wider spread.

Area of Science:

  • Virology
  • Immunology
  • Clinical Medicine

Background:

  • Vaccine-associated paralytic poliomyelitis (VAPP) is a rare but serious complication of oral poliovirus vaccine (OPV).
  • Immunocompromised individuals are at increased risk for VAPP.
  • The emergence of vaccine-related poliovirus (VRPV) infections poses a public health concern.

Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
51.9K
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.1K
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
4.5K
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.3K
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
762
Acute Respiratory Failure-I01:21

Acute Respiratory Failure-I

Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
1.1K