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[Age peculiar by endonasal homeostasis in humans.]

V V Petrov1, D L Tepliy2

  • 1South-Russian humanitarian Institute, 56 a, N. Ostrovskogo str., Astrakhan, 414045, Russian Federatin; glavlor@rambler.ru.

Advances in Gerontology = Uspekhi Gerontologii
|January 12, 2018
PubMed

Insights

This study examines age-related changes in the nasal cavity's protective functions and homeostasis. Understanding these dynamics is crucial for both experimental physiology and clinical medicine.

Area of Science:

  • Physiology
  • Nasal Cavity Homeostasis
  • Developmental Biology

Background:

  • The nasal cavity's protective functions are key to its homeostasis.
  • Endonasal homeostasis undergoes specific changes during postnatal development and involution.
  • Studying these changes has significant scientific and practical implications.

Purpose of the Study:

  • To investigate the age-related dynamics of functional indicators of endonasal homeostasis in humans.
  • To analyze buffer properties and morphological features of nasal secretions across different age groups.
  • To explore age gradients and the role of entropy in endonasal homeostasis.

Main Methods:

  • Comparative analysis of functional indicators.
  • Examination of age dynamics during postnatal development.
  • Application of the doctrine of entropy.

Main Results:

  • Data on age-specific changes in endonasal homeostasis indicators were collected.
  • Buffer properties and morphological characteristics of nasal secret show distinct age-related patterns.
  • Age gradients in functional parameters were identified.

Conclusions:

  • Endonasal homeostasis exhibits significant age-related variations.
  • These findings are valuable for understanding nasal physiology and developing clinical applications.
  • The study highlights the importance of age dynamics in nasal protective functions.

Keywords:
developmental physiologyentropygerontologygradienthomeostasisinvolutionnasal cavitynasal mucusontogeny

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