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Related Concept Videos

Absolute and Local Extreme Values01:22

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The highest and lowest values of a function, relative to a reference axis, are known as extreme values. These include absolute maximum and absolute minimum values, which represent the highest and lowest points the function reaches across its entire domain. Within a restricted portion of the function, the highest and lowest values are referred to as local maximum and local minimum values, respectively.Periodic functions, such as sine and cosine, show extreme values at infinitely many points due...
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Coping strategies are methods people use to manage, tolerate, or reduce the effects of stressors. These strategies involve both behavioral and psychological actions to handle stressful situations. One common approach is problem-focused coping, which aims to change or eliminate the source of stress rather than merely addressing its consequences. This method involves taking direct action to resolve the issue causing stress.
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Related Experiment Video

Updated: Feb 15, 2026

Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats
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Tissue expanders with a focus on extremity reconstruction.

Abdul R Arain1, Keegan Cole1, Christopher Sullivan2

  • 1a Resident, Division of Orthopaedic Surgery , Albany Medical Center , Albany , NY, USA.

Expert Review of Medical Devices
|January 12, 2018
PubMed
Summary
This summary is machine-generated.

Tissue expansion offers a cost-effective solution for managing difficult-to-close wounds, reducing hospital stays and infection rates. External tissue expanders are predicted to increase in use, potentially decreasing the need for complex flap surgeries.

Keywords:
DermaCloseInternal tissue expansionSure closureTop closureTy-Rapsdynamic wound closureexternal tissue expansionproxidermsilver bullet wound closure devicevessel loops

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Area of Science:

  • Plastic Surgery
  • Wound Management
  • Biomaterials

Background:

  • Acute traumatic or surgical wounds pose significant morbidity, mortality, and economic burdens.
  • Primary wound closure is often not feasible, necessitating alternative strategies.
  • Soft tissue expansion has emerged as a valuable technique for wound closure, avoiding complex plastic surgery.

Purpose of the Study:

  • To review the history, biomechanics, and clinical applications of tissue expanders.
  • To compare traditional internal and contemporary external tissue expanders.
  • To analyze the advantages, disadvantages, and outcomes of various tissue expansion methods.

Main Methods:

  • Comprehensive literature review of studies published after 1990.
  • Analysis of case series with Level IV evidence.
  • Data collection on clinical outcomes, cost-effectiveness, and patient recovery.

Main Results:

  • Tissue expanders can reduce costs, shorten wound closure times, decrease hospital stays, and lower infection rates.
  • External tissue expanders show promise for increased future utilization.
  • Understanding expander-specific advantages and disadvantages is crucial for optimizing patient outcomes.

Conclusions:

  • Tissue expansion is an effective alternative for managing complex wounds.
  • Further comparative studies on tissue expander cost-effectiveness are warranted.
  • The trend towards external expanders may reduce reliance on more invasive surgical procedures.