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High Density Event-related Potential Data Acquisition in Cognitive Neuroscience
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Auditory P300 event-related potential: Normative data in the Indian population
N A Uvais1, S Haque Nizamie2, Basudeb Das2
1Department of Psychiatry, Iqraa International Hospital and Research Centre, Calicut, Kerala, India.
Neurology India
|January 12, 2018
Summary
This study established normative data for auditory P300 event-related potentials in the Indian population aged 10-50. The P300 amplitude showed significant age-related differences, providing a crucial reference for neurological research.
Area of Science:
- Neuroscience
- Cognitive Electrophysiology
Background:
- The P300 event-related potential is a valuable neurophysiological marker.
- Establishing normative data is essential for accurate clinical interpretation.
Purpose of the Study:
- To generate normative data for auditory P300 event-related potentials in the Indian population across different age groups.
- To provide a reference for identifying P300 abnormalities in psychiatric disorders.
Main Methods:
- Auditory P300 event-related potentials were recorded from healthy Indian participants aged 10-50 years using an oddball paradigm.
- P300 amplitude and latency were analyzed at frontal (Fz), central (Cz), and parietal (Pz) electrode sites.
Main Results:
- Multivariate analysis revealed significant differences in P300 amplitude across age groups at Fz, Cz, and Pz.
- A trend towards significant age-related differences was observed for P300 latency, particularly at Fz.
Conclusions:
- A normative database for P300 amplitude and frequency was successfully generated for the Indian population at Fz, Cz, and Pz.
- This database will serve as a vital reference for future research on psychiatric disorders in India.
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