Related Experiment Video
Updated: Feb 15, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
Pediatric Appendicitis: Association of Chief Complaint With Missed Appendicitis
Zachary Drapkin1,2, Jennifer Dunnick3, Troy E Madsen2
1From the Division of Emergency Medicine, Department of Pediatrics.
Insights
Nonspecific chief complaints at emergency department triage increase the risk of missed appendicitis diagnoses in children. A chief complaint suggestive of appendicitis reduces this diagnostic error.
Area of Science:
- Pediatric Emergency Medicine
- Diagnostic Accuracy
- Surgical Outcomes
Background:
- Appendicitis is a common surgical emergency in children.
- Timely diagnosis is crucial to prevent complications.
- Emergency department (ED) triage chief complaints may influence diagnostic pathways.
Purpose of the Study:
- To evaluate the association between ED triage chief complaints and the rate of missed appendicitis in pediatric patients.
- To determine if chief complaint type impacts the likelihood of delayed appendicitis diagnosis.
Main Methods:
- Retrospective chart review of pediatric patients diagnosed with appendicitis over a 5-year period.
- Analysis of ED chief complaints, classifying them as 'suggestive of appendicitis' or 'nonspecific'.
- Evaluation of missed appendicitis diagnoses based on initial vs. subsequent ED visits within 7 days.
Main Results:
- 1680 patients with appendicitis were reviewed; 4% had prior ED visits within a week.
- Patients with nonspecific chief complaints had a higher rate of missed appendicitis (8.8%) compared to those with suggestive complaints (3.8%).
- No significant differences in age, sex, white blood cell count, or fever were found between initially diagnosed and multiply visited patients.
Conclusions:
- A chief complaint less suggestive of appendicitis is linked to a higher incidence of missed diagnoses in pediatric EDs.
- Findings suggest that the initial chief complaint may contribute to anchoring bias, impacting appendicitis diagnosis.
- Emphasizes the importance of considering appendicitis even with nonspecific presenting complaints.
Objectives:
We evaluated the association between the emergency department (ED) triage chief complaint and rate of missed appendicitis in children.
Methods:
We performed a retrospective chart review of patients who presented to a pediatric ED and were diagnosed with appendicitis over 5 years (July 1, 2009 to June 30, 2014). We reviewed the medical record for any additional ED visits in the 7 days preceding the diagnosis of appendicitis. Triage chief complaints were classified as "suggestive of appendicitis" (abdominal pain, right lower quadrant pain, or rule out appendicitis) or "nonspecific" (fever, vomiting, dehydration, etc). We evaluated the association between triage chief complaint and missed diagnosis of appendicitis.
Results:
We reviewed 1680 patients with appendicitis. In 67 (4%) cases, patients had at least 1 additional ED visit during the week preceding the diagnosis of appendicitis. When comparing those diagnosed with appendicitis at their initial ED visit to those diagnosed after multiple visits, we found no difference in age (9.9 vs 10.1 years, P = 0.665), sex (55.7% vs 49.3% male, P = 0.291), white blood cell count (14.4 vs 12.3 × 103/L, P = 0.115), or presence of fever (19.9% vs 19.4%, P = 0.920). Of patients with a triage chief complaint that was suggestive of appendicitis, 3.8% were missed on their initial ED visit versus 8.8% of those with a nonspecific triage chief complaint (odds ratio, 2.46; 95% confidence interval, 1.1-5.6).
Conclusions:
A triage chief complaint less suggestive of appendicitis was associated with a higher rate of missed appendicitis in a pediatric ED. Our findings further confirm the potential impact of anchoring bias by a triage chief complaint when attempting to diagnose appendicitis.
Related Concept Videos
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Associative Learning
Classical conditioning, also known...
Association Areas of the Cortex
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Pharmacokinetics in Pediatric Patients: Drug Excretion
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...

