Proof-of-concept study of an at-home, engaging, digital intervention for pediatric ADHD

Naomi O Davis1, Jeffrey Bower2, Scott H Kollins1

  • 1Department of Psychiatry and Behavioral Sciences, School of Medicine, Duke University, Durham, North Carolina, United States of America.

Plos One
|January 12, 2018
PubMed

Insights

A new digital treatment showed promise for improving attention and working memory in children with Attention-Deficit/Hyperactivity Disorder (ADHD). This study suggests potential for digital interventions in managing ADHD-related cognitive deficits.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Digital Therapeutics

Background:

  • Pharmacological and behavioral therapies have limited efficacy for neurocognitive impairments in Attention-Deficit/Hyperactivity Disorder (ADHD).
  • Existing cognitive training programs demonstrate restricted effectiveness in addressing ADHD-related cognitive deficits.
  • Novel digital interventions are needed to target specific cognitive processes implicated in ADHD.

Purpose of the Study:

  • To assess the acceptability of a novel digital treatment for children with ADHD.
  • To explore the preliminary outcomes of a digital intervention targeting cognitive functions in ADHD.
  • To evaluate treatment satisfaction and cognitive improvements in a pediatric ADHD population.

Main Methods:

  • A proof-of-concept study involving 40 children with ADHD and 40 controls.
  • Participants completed a 28-day at-home digital treatment regimen.
  • Neuropsychological assessments and treatment satisfaction measures were administered pre- and post-intervention.

Main Results:

  • High adherence (84%) and strong intervention appeal were reported.
  • Significant improvements in attention were observed in the ADHD group and a high-severity subgroup.
  • Enhancements in spatial working memory were noted for the ADHD group and the high-severity subgroup.

Conclusions:

  • The digital treatment shows preliminary efficacy in improving attention and working memory in children with ADHD.
  • Findings support the potential of this digital approach for enhancing cognitive functions in pediatric ADHD.
  • Further large-scale randomized controlled trials are warranted to confirm efficacy and functional impact.
Abstract

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