[Correlation between of aortic dissection onset and climate change]

Area of Science:

• Cardiovascular Diseases
• Environmental Health
• Epidemiology

Background:

• Acute aortic dissection is a life-threatening condition.
• Understanding environmental triggers like climate change is crucial for public health.
• Previous research has not extensively explored the link between climate and aortic dissection.

Purpose of the Study:

• To investigate the association between climate variations and the incidence of acute aortic dissection.
• To determine if seasonal and monthly temperature changes influence aortic dissection occurrence.

Main Methods:

• Retrospective analysis of 345 acute aortic dissection patients (2005-2015).
• Collection of meteorological data including temperature, pressure, rainfall, and humidity.
• Statistical analysis using rank-sum tests and generalized additive models to assess climate-dissection relationships.

Main Results:

• Aortic dissection incidence showed seasonal variation, with higher rates in winter than summer.
• Monthly analysis indicated a peak in December and a low in July.
• A statistically significant increase in dissection probability was observed with decreasing mean temperatures (RR=1.01).

Conclusions:

• The onset of aortic dissection is influenced by seasonal and monthly climate patterns.
• Lower temperatures correlate with a higher incidence of aortic dissection.
• Climate change may represent a modifiable risk factor for aortic dissection.