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Updated: Feb 15, 2026

Environmental Modulations of the Number of Midbrain Dopamine Neurons in Adult Mice
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The structural determinants of the bitopic binding mode of a negative allosteric modulator of the dopamine D2

Christopher J Draper-Joyce1, Mayako Michino2, Ravi Kumar Verma2

  • 1Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville campus), 399 Royal Parade, Parkville, VIC 3052, Australia.

Biochemical Pharmacology
|January 13, 2018
PubMed

Keywords:
Allosteric modulationBitopic ligandsDopamine receptorG protein-coupled receptorMolecular dynamics simulationsMutagenesis

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