Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genetics of Speciation02:16

Genetics of Speciation

22.0K
Speciation is the evolutionary process resulting in the formation of new, distinct species—groups of reproductively isolated populations.
22.0K
What is Population Genetics?01:25

What is Population Genetics?

65.0K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
65.0K
What is Genetic Engineering?00:49

What is Genetic Engineering?

80.4K
Overview
80.4K
Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

9.3K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
9.3K
Types of Genetic Transfer Between Organisms02:18

Types of Genetic Transfer Between Organisms

31.2K
Genetic transfer occurs when genetic information is passed from one organism to another. It occurs via two mechanisms: vertical gene transfer and horizontal gene transfer. Vertical gene transfer occurs when genetic information is transferred from one generation to the next, which happens much more frequently than horizontal gene transfer. Both sexual and asexual reproduction are forms of vertical gene transfer, where one or more organisms pass some or all of their genome onto their progeny.
31.2K
Mutation, Gene Flow, and Genetic Drift01:09

Mutation, Gene Flow, and Genetic Drift

64.7K
In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).
64.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Second Family with Autosomal Dominant Burning Feet Syndrome.

Annals of the New York Academy of Sciences·2017
Same author

Hereditary Neuralgic Amyotrophy: Mutation Analysis of Candidate Genes.

Annals of the New York Academy of Sciences·2017
Same author

Is essential tremor a single entity?

European journal of neurology·2017
Same author

GABA(A) receptor- and GABA transporter polymorphisms and risk for essential tremor.

European journal of neurology·2011
Same author

The outer arterial wall layers are primarily affected in spontaneous cervical artery dissection.

Neurology·2011
Same author

Sensitivity of neurovascular ultrasound for the detection of spontaneous cervical artery dissection.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2008

Related Experiment Video

Updated: Feb 15, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.9K

[Genetics of tremor].

G Kuhlenbäumer1, F Hopfner2

  • 1Klinik für Neurologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Christian-Albrechts-Universität Kiel, Arnold-Heller-Str. 3, 24105, Kiel, Deutschland. g.kuhlenbaeumer@neurologie.uni-kiel.de.

Der Nervenarzt
|January 13, 2018
PubMed
Summary

The genetics of essential tremor (ET) remain elusive despite extensive research. Identifying tremor in movement disorders is crucial for accurate differential diagnosis, aiding in conditions like hereditary dystonia and ataxia.

Keywords:
Essential tremorHereditary ataxiaHereditary dystoniaMonogenic tremorSpastic spinal paralysis

More Related Videos

Forward Genetic Approaches in Chlamydia trachomatis
09:03

Forward Genetic Approaches in Chlamydia trachomatis

Published on: October 23, 2013

13.3K
FISH for Pre-implantation Genetic Diagnosis
07:34

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

37.9K

Related Experiment Videos

Last Updated: Feb 15, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.9K
Forward Genetic Approaches in Chlamydia trachomatis
09:03

Forward Genetic Approaches in Chlamydia trachomatis

Published on: October 23, 2013

13.3K
FISH for Pre-implantation Genetic Diagnosis
07:34

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

37.9K

Area of Science:

  • Neurology
  • Genetics
  • Movement Disorders

Background:

  • Tremor is a common symptom across various diseases, including essential tremor (ET).
  • Understanding the genetic basis of ET is critical for diagnosis and treatment.
  • ET can present as a distinct disease entity.

Purpose of the Study:

  • To investigate the genetics of essential tremor.
  • To explore the differential diagnosis of monogenic diseases presenting with tremor.
  • To highlight the diagnostic value of tremor in movement disorders.

Main Methods:

  • Comprehensive literature review.
  • Searched clinical genetics databases (OMIM, GeneReviews, MDSGene).
  • Consulted German Neurological Society (DGN) guidelines.

Main Results:

  • The genetic underpinnings of essential tremor remain largely unresolved.
  • Tremor is a significant symptom for diagnosing various movement disorders.
  • Subtle tremors may be underreported in existing disorder descriptions.

Conclusions:

  • Advancing essential tremor genetics necessitates refined phenotyping and subgroup stratification.
  • Tremor assessment is vital in all movement disorder evaluations.
  • Recognizing tremor aids in diagnosing hereditary dystonia, ataxia, and spastic paraplegia.