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Updated: Feb 15, 2026

Contrast Enhanced Vessel Imaging using MicroCT
Published on: January 27, 2011
Investigation of an appropriate contrast-enhanced CT protocol for young patients following the Fontan operation
Motoo Nakagawa1, Yoshiyuki Ozawa2, Norikazu Nomura3
1Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Japan. lmloltlolol@gmail.com.
Insights
Contrast-enhanced CT scans are adequate for evaluating children after the Fontan operation. Both 60-second and 70-second delayed phases effectively assess intraconduit patency in congenital heart disease patients.
Area of Science:
- Medical Imaging
- Pediatric Cardiology
- Radiology
Background:
- Children with congenital heart diseases (CHDs) require post-Fontan operation follow-up.
- Complications like conduit occlusion necessitate imaging surveillance.
- Contrast-enhanced CT is a key tool for assessing these complications.
Purpose of the Study:
- To develop an optimal contrast-enhanced CT protocol.
- To evaluate the adequacy of delayed scanning phases for children post-Fontan operation.
- To ensure accurate assessment of conduit patency.
Main Methods:
- 29 dual-source CT examinations were performed on 26 pediatric patients (aged 2-11 years) post-Fontan operation.
- Contrast medium was administered intravenously.
- Scanning occurred at 60 or 70-second delayed phases to evaluate conduit enhancement.
Main Results:
- Conduit enhancement showed similar CT numbers at both 60 and 70 seconds (185 ± 46 HU vs. 185 ± 31 HU).
- Statistical analysis revealed no significant difference between the two delayed phases (P=0.97).
- Both phases provided comparable visualization of the conduits.
Conclusions:
- Both 60-second and 70-second delayed phases are suitable for contrast-enhanced CT.
- These protocols adequately evaluate intraconduit patency in pediatric patients after the Fontan operation.
- The findings support the use of either delayed phase for routine follow-up imaging.
Purpose:
Children with congenital heart diseases (CHDs) may need to be followed up with contrast-enhanced CT following the Fontan operation because complications such as the occlusion of conduits may occur. The purpose of the present study was to develop an adequate contrast-enhanced CT protocol for children with CHD following the Fontan operation.
Materials And Methods:
Between July 2012 and July 2017, 29 CT examinations for 26 patients aged 2-11 years (median 5 years) with CHD following the Fontan operation were performed using dual-source CT. A non-ionized contrast medium was injected through the dorsum manus vein. Scanning began 60 or 70 s after the start of the injection. The delayed phase was randomly selected to be 60 s in 14 cases and 70 s in 15 cases. We evaluated the enhancement of conduits following the Fontan operation at delayed phases.
Results:
The CT numbers of conduits at 60 and 70 s were 185 ± 46 and 185 ± 31 HU, respectively (P = 0.97).
Conclusion:
In contrast-enhanced CT for children after the Fontan operation, both of the delayed phases (60 and 70 s) appeared to be adequate for evaluating intraconduit patency.
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