Related Experiment Video
Updated: Feb 15, 2026

A Virtual Machine Platform for Non-Computer Professionals for Using Deep Learning to Classify Biological Sequences of Metagenomic Data
Published on: September 25, 2021
Graphical classification of DNA sequences of HLA alleles by deep learning
Jun Miyake1,2, Yuhei Kaneshita3, Satoshi Asatani3
1Graduate School of Engineering Science, Osaka University, 1-3 Machikane-Yama, Toyonaka, Osaka, 560-8531, Japan. jun_miyake@bpe.es.osaka-u.ac.jp.
Abstract:
Alleles of human leukocyte antigen (HLA)-A DNAs are classified and expressed graphically by using artificial intelligence "Deep Learning (Stacked autoencoder)". Nucleotide sequence data corresponding to the length of 822 bp, collected from the Immuno Polymorphism Database, were compressed to 2-dimensional representation and were plotted. Profiles of the two-dimensional plots indicate that the alleles can be classified as clusters are formed. The two-dimensional plot of HLA-A DNAs gives a clear outlook for characterizing the various alleles.
Related Concept Videos
Multiple Allele Traits
Lethal Alleles
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
Solving Equations Graphically
Graphical Representation of Inequalities
Solving Inequalities Graphically
Cis-regulatory Sequences

