Related Experiment Video
Updated: Feb 15, 2026

09:25
The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse
Published on: May 31, 2016
20.3K
Fatigue and related comorbidities, active component, U.S. Armed Forces, 2007-2016.
MSMR
|January 13, 2018
Summary
Fatigue is a common diagnosis in the U.S. military, affecting 18.1 per 1,000 person-years. Identifying associated conditions like mental disorders can speed up diagnosis and treatment for service members.
Area of Science:
- Military medicine
- Public health surveillance
- Clinical epidemiology
Background:
- Fatigue is a prevalent symptom in the general population, often indicating underlying health issues.
- Understanding fatigue's incidence and impact within the military is crucial for service member health.
- Previous research has not fully characterized fatigue burden in active military personnel.
Purpose of the Study:
- To determine the incidence and burden of fatigue in active component U.S. military members.
- To analyze comorbidities associated with fatigue and their impact on military health.
- To identify key conditions linked to fatigue for improved diagnostic and treatment strategies.
Main Methods:
- Utilized data from the Defense Medical Surveillance System (DMSS) for active component military members.
- Analyzed incident fatigue cases from January 2007 to December 2016.
- Conducted a subanalysis (2012-2014) to assess comorbidity burden and associations with fatigue.
Main Results:
- Identified 211,213 incident fatigue cases, with an overall incidence rate of 18.1 per 1,000 person-years (2007-2016).
- In 2013, mental disorders and musculoskeletal diseases accounted for 35% of medical encounters and 40% of hospital days for fatigue patients.
- Male hypogonadism, thyroid disorder, and sleep problems showed the highest adjusted odds ratios for fatigue.
Conclusions:
- Fatigue is a common diagnosis with significant incidence and burden among active U.S. military personnel.
- Comorbidities such as mental disorders, musculoskeletal diseases, and specific endocrine/sleep issues are strongly associated with fatigue.
- Targeting these associated conditions can facilitate earlier diagnosis and treatment for service members experiencing fatigue.
Related Concept Videos
Fatigue
874
Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
874
Muscles that Move the Arm
4.9K
Nine muscles are involved in arm movements. Two of these, the pectoralis major and latissimus dorsi, originate from the axial skeleton and are called axial muscles. The other seven originate from the scapula and are called the scapular muscles.
The pectoralis major has two origins. Its clavicular head originates on the medial half of the clavicle. In contrast, the sternocostal head originates on the costal cartilages of ribs 1-6, the sternum, and the aponeurosis of the external oblique of the...
The pectoralis major has two origins. Its clavicular head originates on the medial half of the clavicle. In contrast, the sternocostal head originates on the costal cartilages of ribs 1-6, the sternum, and the aponeurosis of the external oblique of the...
4.9K
Muscle Recovery and Fatigue
4.3K
Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...
4.3K
Fatigue Strength of Concrete
599
Fatigue, in the context of materials science and engineering, refers to the weakening or failure of a material caused by repeatedly applied loads, even if these loads are below the strength limit of the material. Fatigue strength in concrete is a critical property that influences its durability and longevity. Concrete can fail in two ways due to fatigue. Static fatigue or creep rupture occurs under a constant load or one that increases slowly. The other failure mode is due to cyclical or...
599
Components of Language
836
Language, whether spoken, signed, or written, consists of specific components: lexicon and grammar. The lexicon is the vocabulary of a language, comprising its words. Grammar is the set of rules used to convey meaning through the lexicon. For example, English grammar adds “-ed” to most verbs to indicate past tense. Words are formed by combining phonemes, which are the basic sound units of a language. Different languages have different sets of phonemes (e.g., “ah” vs.
836
Components of Stress
559
Stress analysis under multiple loading conditions is intricate, necessitating a comprehensive grasp of normal and shearing stresses. Consider a small cube at point O, subjected to stress on all six faces, visible or not. Normal stress components σx, σy, σz act perpendicularly to the x, y, and z axes. Shearing stress components τxy and τxz are exerted on faces perpendicular to these axes.
Interestingly, the hidden cube faces also experience these stresses, equal and...
Interestingly, the hidden cube faces also experience these stresses, equal and...
559

