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Fc and C3b receptor changes on mouse peritoneal leucocytes following stimulation with an extract of Ascaris suum
Zentralblatt Fur Bakteriologie, Mikrobiologie, Und Hygiene. Series A, Medical Microbiology, Infectious Diseases, Virology, Parasitology
|August 1, 1985
Abstract:
Changes in IgG-Fc and IgM-C3b receptors of mouse peritoneal leucocytes after in vivo stimulation with Ascaris suum adult extract were studied. Erythrocyte IgG-Fc rosettes were found to initially be decreased with A. suum stimulated neutrophils, eosinophils and macrophages in comparison with nonstimulated cells. IgG-Fc rosettes then increased with time and remained high for a 60 min exposure time. IgM-C3b rosette formation was lower with A. suum stimulated leucocytes throughout 60 min of exposure and dropped off dramatically after 30 min. Unstimulated leucocytes formed IgM-C3b rosettes sooner and maintained them at higher levels for a longer period of time than stimulated cells.