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Kaempferol alleviates LPS-induced neuroinflammation and BBB dysfunction in mice via inhibiting HMGB1 release and

Xiao Cheng1, Ying-Lin Yang2, Huan Yang2

  • 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China; Beijing Key Laboratory of Drug Target Identification and New Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.

International Immunopharmacology
|January 13, 2018
PubMed

Keywords:
Blood-brain barrier (BBB)High-mobility group protein 1 (HMGB1)KaempferolLipopolysaccharide (LPS)Myeloid differentiation factor 88 (MyD88)Toll-like receptor-4 (TLR4)

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