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Relative wall thickness analysis by two-dimensional echocardiography.

P S Douglas, N Reichek, T Plappert

    American Heart Journal
    |November 1, 1985
    PubMed
    Summary
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    Two-dimensional echocardiography (2DE) offers a more accurate assessment of left ventricular hypertrophy (LVH) than M-mode echocardiography. 2DE RWT improves diagnosis of conditions like cardiomyopathy and aortic regurgitation.

    Area of Science:

    • Cardiology
    • Medical Imaging
    • Diagnostic Techniques

    Background:

    • M-mode echocardiography's relative wall thickness (RWT) is a common index for left ventricular hypertrophy (LVH).
    • Limitations exist in M-mode's spatial orientation and sampling, potentially affecting RWT accuracy.
    • Two-dimensional echocardiography (2DE) offers improved tomographic sampling and spatial orientation.

    Purpose of the Study:

    • To compare the diagnostic value of 2DE-derived RWT versus M-mode RWT.
    • To assess if 2DE enhances RWT's utility in evaluating LVH, particularly in conditions like volume overload and cardiomyopathy.
    • To determine the correlation and agreement between M-mode and 2DE RWT measurements.

    Main Methods:

    • Retrospective analysis of echocardiographic data from 69 subjects.

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  • Inclusion criteria: normal subjects, aortic stenosis, aortic regurgitation, and congestive cardiomyopathy.
  • Comparison of M-mode and 2DE RWT measurements at end-diastole and end-systole.

    • Main Results:

    • M-mode RWT showed weak correlation with 2DE RWT (r=0.62 end-diastole, r=0.81 end-systole).
    • M-mode RWT values differed significantly from 2DE RWT (end-systolic: higher; end-diastolic: lower; p<0.001).
    • M-mode RWT failed to differentiate between cardiomyopathy, aortic regurgitation, and normal subjects in some cases.

    Conclusions:

    • M-mode and 2DE echocardiographic analyses of RWT yield significantly different results.
    • 2DE RWT analysis may provide enhanced diagnostic value for LVH, especially in volume overload and cardiomyopathy.
    • 2DE offers a more reliable assessment of RWT compared to M-mode echocardiography.