Related Experiment Video

Updated: Feb 15, 2026

Technique of Minimally Invasive Transverse Aortic Constriction in Mice for Induction of Left Ventricular Hypertrophy
08:34

Technique of Minimally Invasive Transverse Aortic Constriction in Mice for Induction of Left Ventricular Hypertrophy

Published on: September 25, 2017

25.6K

Left ventricular hypertrophy and cognitive function: a systematic review

C Restrepo1, S K Patel1,2, V Rethnam1

  • 1The Florey Institute of Neuroscience and Mental Health, Austin Health, Heidelberg, VIC, Australia.

Journal of Human Hypertension
|January 14, 2018
PubMed

Insights

Left ventricular hypertrophy (LVH), a marker of hypertension damage, is linked to cognitive impairment. This review found LVH is associated with poorer memory and executive functions in adults over 50.

Area of Science:

  • Cardiology
  • Neurology
  • Gerontology

Background:

  • Cognitive impairment frequently affects patients with hypertension.
  • Left ventricular hypertrophy (LVH) signifies hypertension-related organ damage and predicts cardiovascular events.
  • Existing evidence suggests LVH independently correlates with cognitive decline, even accounting for hypertension.

Purpose of the Study:

  • To systematically review studies investigating cognitive impairment in adults with LVH.
  • To identify specific cognitive domains affected by LVH.
  • To explore potential mechanisms linking LVH and cognitive dysfunction.

Main Methods:

  • Systematic literature search in Ovid MEDLINE, Ovid psycInfo, and PubMed.
  • Inclusion criteria: English language, human studies, adults aged 50+, examining LVH and cognition.
  • Nine studies met the criteria for inclusion in the review.

Main Results:

  • The majority of included studies demonstrated an association between LVH and cognitive performance.
  • Individuals with LVH generally showed lower performance on cognitive tests compared to those without LVH.
  • Memory and executive functions were identified as cognitive domains particularly vulnerable to the presence of LVH.

Conclusions:

  • LVH is associated with impaired cognitive performance, specifically affecting memory and executive functions.
  • Cerebral white matter damage, common in LVH patients, may underlie the observed cognitive dysfunction.
  • These findings highlight the impact of LVH on cognitive health, particularly in older adults.

More Related Videos

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

4.7K
A Pulmonary Trunk Banding Model of Pressure Overload Induced Right Ventricular Hypertrophy and Failure06:47

A Pulmonary Trunk Banding Model of Pressure Overload Induced Right Ventricular Hypertrophy and Failure

Published on: November 29, 2018

10.1K

Related Concept Videos

Cognitive Dissonance01:38

Cognitive Dissonance

Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...
37.5K
Review and Preview01:10

Review and Preview

In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.4K
Review and Preview01:13

Review and Preview

Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.6K
Random and Systematic Errors01:20

Random and Systematic Errors

Scientists always try their best to record measurements with the utmost accuracy and precision. However, sometimes errors do occur. These errors can be random or systematic. Random errors are observed due to the inconsistency or fluctuation in the measurement process, or variations in the quantity itself that is being measured. Such errors fluctuate from being greater than or less than the true value in repeated measurements. Consider a scientist measuring the length of an earthworm using a...
15.4K
Systematic Sampling Method01:17

Systematic Sampling Method

Sampling is a technique to select a portion (or subset) of the larger population and study that portion (the sample) to gain information about the population. Data are the result of sampling from a population. The sampling method ensures that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest.
Systematic sampling is one of the simplest methods...
13.4K
Propagation of Uncertainty from Systematic Error01:10

Propagation of Uncertainty from Systematic Error

The atomic mass of an element varies due to the relative ratio of its isotopes. A sample's relative proportion of oxygen isotopes influences its average atomic mass. For instance, if we were to measure the atomic mass of oxygen from a sample, the mass would be a weighted average of the isotopic masses of oxygen in that sample. Since a single sample is not likely to perfectly reflect the true atomic mass of oxygen for all the molecules of oxygen on Earth, the mass we obtain from this...
1.5K