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Related Concept Videos

Ion Channels01:19

Ion Channels

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The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange.
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
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Common Ion Effect03:24

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Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Châtelier’s principle. Consider the dissolution of silver iodide:
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Precipitation of Ions03:11

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Predicting Precipitation
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Introduction to Membrane Proteins01:16

Introduction to Membrane Proteins

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The cell membrane, or plasma membrane, is an ever-changing landscape. It is described as a fluid mosaic where various macromolecules are embedded in the phospholipid bilayer. Among the macromolecules are proteins. The protein content varies across cell types. For example, mitochondrial inner membranes contain ~76% protein content, while myelin contains ~18% protein content. Individual cells contain many types of membrane proteins—red blood cells contain over 50—and different cell...
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Formation of Complex Ions03:45

Formation of Complex Ions

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A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...
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Ions and Ionic Charges03:27

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In ordinary chemical reactions, the nucleus — which contains the protons and neutrons of each atom and thus identifies the element — remains unchanged. Electrons, however, can be added to atoms by transfer from other atoms, lost by transfer to other atoms, or shared with other atoms. The transfer and sharing of electrons among atoms govern the chemistry of the elements. During the formation of some compounds, atoms gain or lose electrons to form electrically charged particles called...
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Membrane Remodeling of Giant Vesicles in Response to Localized Calcium Ion Gradients
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Membrane Remodeling of Giant Vesicles in Response to Localized Calcium Ion Gradients

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Membrane-Ion Interactions.

Ran Friedman1

  • 1Department of Chemistry and Biomedical Sciences and Centre of Excellence "Biomaterials Chemistry", Linnæus University, Kalmar, Sweden. ran.friedman@lnu.se.

The Journal of Membrane Biology
|January 14, 2018
PubMed
Summary
This summary is machine-generated.

This review covers experimental and computational methods for studying how ions in electrolyte solutions interact with biomembranes. Understanding these membrane-ion interactions is crucial for various biological processes.

Keywords:
Alkali ionsMolecular dynamicsNMRQuadrupole NMRSpecific ion effects

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Area of Science:

  • Biophysics
  • Physical Chemistry
  • Biochemistry

Background:

  • Biomembranes function at interfaces with electrolyte solutions.
  • Ion interactions with lipids influence membrane structure, dynamics, and electrostatics.

Purpose of the Study:

  • To review experimental and computational methods for studying membrane-ion interactions.
  • To survey molecular dynamics simulations applied to membrane-ion systems.
  • To discuss the current understanding and significance of these interactions.

Main Methods:

  • Review of experimental techniques (direct and indirect).
  • Survey of molecular dynamics (MD) simulation studies.
  • Synthesis of current knowledge on membrane-ion interactions.

Main Results:

  • Overview of diverse experimental approaches.
  • Highlighting insights gained from MD simulations.
  • Summarizing the established knowledge on membrane-ion interactions.

Conclusions:

  • Membrane-ion interactions are fundamental to biomembrane function.
  • A combination of experimental and computational methods provides comprehensive insights.
  • Further research continues to refine our understanding of these critical interactions.