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The iridocorneal endothelial syndrome
Luis Silva1, Ahmad Najafi1, Yanin Suwan2
1Einhorn Clinical Research Center, The New York Eye and Ear Infirmary of Mount Sinai, New York, New York, USA.
Survey of Ophthalmology
|January 15, 2018
Summary
Iridocorneal endothelial syndrome involves abnormal corneal cell growth, leading to vision loss and glaucoma. Early diagnosis and treatment, including surgery, are crucial for managing this rare eye condition.
Area of Science:
- Ophthalmology
- Cell Biology
Background:
- Iridocorneal endothelial syndrome (ICES) encompasses Chandler syndrome, progressive iris atrophy, and Cogan-Reese syndrome.
- Characterized by corneal endothelial cell proliferation and migration, leading to ocular complications.
Purpose of the Study:
- To detail the pathophysiology, diagnosis, and management of iridocorneal endothelial syndrome.
- To highlight the role of in vivo confocal microscopy and evolving surgical techniques.
Main Methods:
- Review of clinical findings and diagnostic tools for ICES.
- Discussion of current treatment strategies for corneal edema and secondary glaucoma.
Main Results:
- ICES presents with corneal edema, decompensation, and secondary glaucoma due to cell migration.
- In vivo confocal microscopy aids in diagnosing early or atypical cases.
- Endothelial keratoplasty and glaucoma surgery are primary interventions.
Conclusions:
- ICES requires prompt diagnosis and tailored management for optimal outcomes.
- Advances in surgical techniques improve treatment efficacy for ICES patients.
Keywords:
Chandler's syndromeCogan-Reese syndromecorneal edemaglaucomakeratoplastyprogressive iris atrophyMore Related Videos
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