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Asthma predictive index in relation to respiratory mechanics by impulse oscillometry in recurrent wheezers

T Arikoglu1, S B Batmaz2, D D Yildirim3

  • 1Mersin University, Faculty of Medicine, Department of Pediatric Allergy and Immunology, Mersin, Turkey.

Allergologia Et Immunopathologia
|January 15, 2018
PubMed

Insights

Impulse oscillometry (IOS) can help identify preschool children at high risk for persistent asthma. This lung function test shows diagnostic value in predicting the modified Asthma Predictive Index (mAPI) in wheezing preschoolers.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Diagnostics
  • Asthma Research

Background:

  • Identifying children with persistent asthma is crucial.
  • Recurrent wheezing in preschoolers requires accurate risk assessment.
  • Impulse oscillometry (IOS) is a potential tool for evaluating respiratory function.

Purpose of the Study:

  • To evaluate the diagnostic value of impulse oscillometry (IOS).
  • To predict the modified Asthma Predictive Index (mAPI) in preschoolers with recurrent wheezing.
  • To identify children at high risk for developing persistent asthma.

Main Methods:

  • Enrolled preschool children (3-6 years) with recurrent wheezing.
  • Classified children into two groups based on mAPI criteria.
  • Assessed lung function using impulse oscillometry (IOS).

Main Results:

  • 64% of children were mAPI positive; R5-R20% levels were significantly higher in mAPI-positive children.
  • R5-R20% levels correlated with parental asthma and inhalant sensitization.
  • R5-R20% >14.4 showed 75% sensitivity and 53% specificity for predicting positive mAPI.

Conclusions:

  • Impulse oscillometry (IOS) demonstrates diagnostic value in predicting mAPI.
  • IOS can aid clinicians in identifying high-risk preschool wheezers.
  • This supports the use of IOS for early asthma risk assessment in children.
Abstract

Keywords:
AsthmaAsthma predictive indexImpulse oscillometryPreschoolersWheezing

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