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Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
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Tumefactive Multiple Sclerosis Masquerading as High Grade Glioma.

Michelle Lin1, Patrick Reid1, Joshua Bakhsheshian1

  • 1Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

World Neurosurgery
|January 15, 2018
PubMed
Summary

Tumefactive demyelinating lesions (TDLs) can mimic high-grade gliomas on imaging. This case shows a patient diagnosed with TDL via biopsy, who fully recovered with conservative steroid treatment, avoiding unnecessary surgery.

Area of Science:

  • Neuroscience
  • Neurology
  • Radiology

Background:

  • Tumefactive demyelinating lesions (TDLs) present as large demyelinating lesions in the brain.
Keywords:
AutoimmuneDemyelinationGliomaNeurologyNeurosurgeryOncologyPseudotumor

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  • Radiographically, TDLs can closely resemble high-grade gliomas, complicating diagnosis and treatment decisions.
  • Misdiagnosis can lead to invasive procedures and delayed appropriate management.