Apparent Cognitive Decline as Revealed by an Executive Function Test within a Cohort of Elderly Individuals
Thomas B Shea1, Ruth Remington2
1Department of Biological Sciences, UMass Lowell, Lowell, MA, USA.
Journal of Alzheimer'S Disease : JAD
|January 15, 2018
Abstract:
Alzheimer's disease (AD) can be preceded by subtle memory decline that can last a decade or more before progressing to what would be diagnosed as the mild cognitive impairment stage. During this early stage of decline, individuals and even their caregivers can fail to perceive any serious difficulty or need to consult a physician. Herein, we present evidence in support of these concerns, and demonstrate how this can interfere not only with clinical trials of AD but also those involving cognitive performance of elderly individuals without intentional reference to AD.
Keywords:
Cognitive declineMini-Mental State ExamTrail-making testexecutive functionoutliersself-reportMore Related Videos
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