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Serelaxin for infant heart failure in congenital dilated cardiomyopathy

Patrick O Myers1, Alice Bordessoule2, Cécile Tissot3

  • 11Cardiovascular Surgery,Geneva University Hospitals& Faculty of MedicineGeneva,Switzerland.

Cardiology in the Young
|January 16, 2018
PubMed

Insights

This study details the first compassionate use of serelaxin in an infant with dilated cardiomyopathy. Serelaxin infusion improved cardiac function, allowing successful extracorporeal membrane oxygenation weaning.

Area of Science:

  • Pediatric Cardiology
  • Neonatal Intensive Care
  • Pharmacology

Background:

  • Serelaxin, a human relaxin-15, has shown promise in adult acute heart failure.
  • Its use in pediatric populations, particularly infants, remains unexplored.
  • Dilated cardiomyopathy in infants presents significant therapeutic challenges.

Keywords:
CHDHeart failureinotropic/vasoactive drugs

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