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Updated: Feb 15, 2026

Imaging Serotonergic Fibers in the Mouse Spinal Cord Using the CLARITY/CUBIC Technique
Published on: February 26, 2016
[An unintended diagnosis: Serotonergic toxicity secondary to drug interactions. Case reports]
Elda G Cargnel1, Patricia C Cardoso2, Julián Irigoyen2
1Unidad de Toxicología, Hospital de Niños "Ricardo Gutiérrez", Ciudad Autónoma de Buenos Aires. ecargnel@gmail.com.
Abstract:
Serotonin toxicity is a potentially life-threatening condition associated with increased serotonergic activity in the central nervous system. It is seen with therapeutic medication use, intentional self-poisoning and inadvertent interactions (SSRI-isoniazid). Although this pathology is increasingly common, it is not well recognized by physicians and manifestations may be wrongly attributed to another cause. The aim of this paper is to describe the clinical picture of a patient, to collaborate on diagnosis and to improve medical care of these patients.
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