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Updated: Feb 15, 2026
Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model
Published on: April 1, 2019
Soft tissue volume gain around dental implants using autogenous subepithelial connective tissue grafts harvested from
Ernest Rojo1, Giorgio Stroppa1, Ignacio Sanz-Martin1,2
1Department of Periodontology, Universitat Internacional de Catalunya (UIC), Barcelona, Spain.
Aim:
To compare the soft tissue volume gain (VG) around single tooth implants with subepithelial connective tissue graft (SCTG) from either the lateral palate (LP) or from the tuberosity area (TA).
Methods:
Thirty-two patients with 36 implants with buccal volume deficiencies were randomly assigned to receive SCTG from LP (control group/CG) or TA (test group/TG). Clinical parameters were recorded. VG was evaluated by stereolithography (STL) image superimposition of two intraoral scans (baseline/BL and 3 months after surgery/FU-3). Descriptive analysis was performed for both groups, and for comparisons, Mann-Whitney U test was used.
Results:
In terms of VG values, no statistically significant differences were observed except for values at 6 and 7 mm apically to the healing abutment which favoured the TG. Mean values were 0.69 ± 0.23 mm for CG while TG obtained 0.79 ± 0.10 mm (p = .64). Regarding Keratinized tissue (KT) width statistical significant differences were found favouring TG, which obtained a gain of 0.83 ± 0.61 mm compared with 0.22 ± 0.48 mm for CG (p = .009). Pink esthetic scores resulted in mean values of 10.07 ± 2.19 for the CG, while TG obtained 9.15 ± 2.34.
Conclusions:
Both procedures were effective in increasing soft tissue volume with no statistically significant differences. A longer follow-up is needed to confirm or refute these results.
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