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Updated: Feb 15, 2026

A Micropatterning Assay for Measuring Cell Chirality
Published on: March 11, 2022
Chiral separation of novel iminonaringenin derivatives
Meriem Bouanini1, Nasser Belboukhari1, J Carlos Menéndez2
1Bioactive Molecules and Chiral Separation Laboratory, Faculty of Science and Technology, University of Bechar, Bechar, Algeria.
Abstract:
A series of 4-iminonaringenin derivatives 2-6 have been prepared in good overall yields from a condensation reaction between naringenin and primary amines. The structures of all products were confirmed by ultraviolet, infrared, proton nuclear magnetic resonance, and carbon-13 nuclear magnetic resonance spectroscopic techniques. These derivatives were analyzed by high-performance liquid chromatography using polysaccharide-based chiral stationary phases, namely, Chiralpak IB and Chiralcel OD, using various mobile phases. 2-Propanol showed a high enantioselectivity for naringin and its derivatives using achiral column containing immobilized polysaccharides (Chiralpak IB).
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