Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Benefits of Self-Esteem

Benefits of Self-Esteem

Self-esteem—an individual's overall evaluation of their worth—plays a complex role in psychological functioning and well-being. It is often associated with many positive traits, such as confidence, optimism, and perseverance. Individuals with high self-esteem typically experience better sleep, manage peer pressure more effectively, and report greater life satisfaction. Conversely, low self-esteem has been consistently linked with increased risks of depression, anxiety, and poor...

Limiting Reactant

Limiting Reactant

The relative amounts of reactants and products represented in a balanced chemical equation are often referred to as stoichiometric amounts. However, in reality, the reactants are not always present in the stoichiometric amounts indicated by the balanced equation.

The Number e as a Limit

The Number e as a Limit

The number e is a fundamental constant in calculus, playing a central role in describing continuous change, particularly exponential growth. It is most naturally defined through its relationship with the natural logarithm, which is the inverse of the exponential function with base e. This relationship allows e to be characterized using basic principles of differentiation rather than as an arbitrary numerical constant.A key property of the natural logarithm function, ln x, is that its derivative...

Types of Limits I

Types of Limits I

Limits are a key mathematical concept for understanding how functions behave as their input approaches specific values, particularly when the function is undefined. They help reveal trends and discontinuities by examining the values a function approaches rather than its actual value.One-sided limits focus on the direction from which a value is approached. When a function behaves differently depending on whether the input approaches from the left or the right, the two one-sided limits may not...

Limit Laws I

Limit Laws I

Limit laws provide essential tools for analyzing how functions behave as their input approaches a specific value. These laws are particularly useful when dealing with combinations of functions, provided the individual limits exist. The Sum and Difference Laws state that the limit of the sum or difference of two functions equals the sum or difference of their respective limits:The Product Law asserts that the limit of the product of two functions equals the product of their individual limits:A...

Limits at Infinity

Limits at Infinity

The function that decreases as the input becomes very large provides a clear example of how mathematical functions can behave at extreme values. When the input increases continuously, the output becomes smaller and smaller, getting closer to a particular fixed value. Although the output never actually reaches this value, it moves nearer to it without limit. This behavior is a fundamental concept in understanding how functions behave as the input grows indefinitely. The graphical representation...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Reducing False-Positives Due to Urinary Stagnation in the Prostatic Urethra on 18 F-DCFPyL PSMA PET/CT With MRI.

Clinical nuclear medicine·2024

Same author

PRECISE Version 2: Updated Recommendations for Reporting Prostate Magnetic Resonance Imaging in Patients on Active Surveillance for Prostate Cancer.

European urology·2024

Same author

Automated prostate gland segmentation in challenging clinical cases: comparison of three artificial intelligence methods.

Abdominal radiology (New York)·2024

Same author

Evaluating Diagnostic Accuracy and Inter-reader Agreement of the Prostate Imaging After Focal Ablation Scoring System.

European urology open science·2024

Same author

A Phase 1 Trial of Salvage Stereotactic Body Radiation Therapy for Radiorecurrent Prostate Cancer After Brachytherapy.

International journal of radiation oncology, biology, physics·2024

Same author

Localized high-risk prostate cancer harbors an androgen receptor low subpopulation susceptible to HER2 inhibition.

medRxiv : the preprint server for health sciences·2024

Search research articles

Related Experiment Video

Updated: Feb 15, 2026

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

Targeted biopsy: benefits and limitations.

Stephanie D Purnell¹, Jonathan B Bloom¹, Vladimir Valera¹

¹Urologic Oncology Branch.

Current Opinion in Urology

|January 16, 2018

Summary

Multiparametric MRI and fusion-guided biopsies improve the detection of significant prostate cancers, reducing unnecessary treatments. Upfront MRI is cost-effective, aiding in treatment decisions for all patients.

More Related Videos

Human Blastocyst Biopsy and Vitrification

Human Blastocyst Biopsy and Vitrification

Published on: July 26, 2019

A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications

A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications

Published on: September 16, 2022

Related Experiment Videos

Last Updated: Feb 15, 2026

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

Human Blastocyst Biopsy and Vitrification

Human Blastocyst Biopsy and Vitrification

Published on: July 26, 2019

A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications

A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications

Published on: September 16, 2022

Area of Science:

Urology
Radiology
Oncology

Background:

Multiparametric MRI (mpMRI) and fusion-guided biopsies are increasingly utilized in urologic practice.
The optimal timing for incorporating mpMRI into the diagnostic workup remains under discussion.

Purpose of the Study:

To review the current literature on the role of mpMRI and fusion-guided biopsies in urologic practice.
To evaluate the impact of these technologies on cancer detection and treatment strategies.

Main Methods:

Literature review of studies investigating mpMRI and fusion-guided biopsies.
Analysis of data regarding cancer detection rates, risk stratification, and cost-effectiveness.

Main Results:

Fusion biopsies increase the detection of clinically significant cancers and decrease the diagnosis of low-risk disease.
mpMRI provides benefits for both biopsy-naïve patients and those with prior negative biopsies in treatment strategy determination.
Cost-analysis models suggest upfront mpMRI is more cost-effective, considering missed cancers and treatment courses.

Conclusions:

Fusion biopsies offer superior accuracy over systematic biopsies for cancer grading.
These techniques are valuable for identifying appropriate candidates for active surveillance and monitoring disease progression.
Integrating mpMRI and fusion biopsies enhances diagnostic accuracy and patient management in urologic oncology.