Stroke After Minor Head Trauma in Infants and Young Children With Basal Ganglia Calcification: A Lenticulostriate

Jatinder Singh Goraya1, Shivankshi Berry1, Kavita Saggar2

  • 11 Department of Pediatrics, Division of Pediatric Neurology, Ludhiana, Punjab, India.

Insights

Basal ganglia stroke in infants may be linked to calcified arteries and minor head trauma. This condition, basal ganglia calcification, can lead to neurological deficits, though some infants recover.

Area of Science:

  • Neurology
  • Pediatrics
  • Radiology

Background:

  • Basal ganglia stroke is a serious condition in infants.
  • Calcification in the basal ganglia may indicate underlying vascular abnormalities.

Purpose of the Study:

  • To investigate the association between basal ganglia stroke, minor head injury, and basal ganglia calcification in children.
  • To identify risk factors and outcomes in pediatric basal ganglia stroke.

Main Methods:

  • Retrospective chart review of children diagnosed with basal ganglia stroke.
  • Analysis of computed tomography (CT) scans for basal ganglia calcification.
  • Review of medical history for preceding minor head trauma.
  • Magnetic resonance imaging (MRI) to confirm infarcts.

Main Results:

  • Eighteen of twenty pediatric patients with basal ganglia stroke had basal ganglia calcification on CT scans.
  • Minor head trauma preceded stroke in 18 patients.
  • MRI confirmed basal ganglia infarcts in 18 infants.
  • Outcomes varied, with 9 achieving good recovery and 7 having persistent deficits.

Conclusions:

  • Basal ganglia calcification, likely representing mineralized lenticulostriate arteries, is a marker for lenticulostriate vasculopathy.
  • Abnormal lenticulostriate vessels are susceptible to injury and thrombosis following minor head trauma, leading to stroke.
  • Early identification and management are crucial for improving outcomes in pediatric basal ganglia stroke.

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