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Portable FAIMS: Applications and Future Perspectives.

Michael T Costanzo1, Jared J Boock2, Robin H J Kemperman3

  • 1Breathtec Biomedical, Inc.; Gainesville, FL 32641.

International Journal of Mass Spectrometry
|January 17, 2018
PubMed
Summary

Field asymmetric ion mobility spectrometry (FAIMS) offers a portable, cost-effective solution for in situ analysis. This technology complements miniaturized mass spectrometry (MMS) and enhances field research capabilities.

Keywords:
BiomedicalDMSEnvironmentalFAIMSLaw EnforcementPortable

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Area of Science:

  • Analytical Chemistry
  • Spectrometry
  • Instrumentation

Background:

  • Miniaturized mass spectrometry (MMS) is suitable for field-portable applications.
  • Field asymmetric ion mobility spectrometry (FAIMS) enables in situ analysis, bringing laboratory capabilities to the field.
  • FAIMS operates at atmospheric pressure, offering a significant advantage for portability compared to mass spectrometry (MS).

Purpose of the Study:

  • To discuss considerations, uses, and applications of portable FAIMS instrumentation.
  • To explore the benefits of portable FAIMS for various scientific fields.
  • To highlight FAIMS as a complementary technique to MMS for field analysis.

Main Methods:

  • Discussion of portable FAIMS instrumentation.
  • Comparison of FAIMS and MMS portability.
  • Exploration of FAIMS advantages for field deployment.

Main Results:

  • FAIMS is uniquely suited for portability due to its atmospheric pressure operation.
  • Portable FAIMS offers simplicity, lower cost, and high throughput, compensating for potential performance trade-offs.
  • Field FAIMS can be coupled with conventional MS for method development and validation.

Conclusions:

  • Portable FAIMS instrumentation is a promising technology for in situ analysis.
  • FAIMS enhances field research by providing a robust, user-friendly, and cost-effective analytical tool.
  • The development and acceptance of portable FAIMS will benefit numerous scientific fields through increased accessibility and convenience.