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Label-free Single Molecule Detection Using Microtoroid Optical Resonators
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Label-Free Optical Biodetection of Pathogen Virulence Factors in Complex Media Using Microtoroids with

Pelin Toren1, Erol Ozgur1, Mehmet Bayindir1

  • 1Institute of Materials Science and Nanotechnology, §UNAM-National Nanotechnology Research Center, and ‡Department of Physics, Bilkent University , 06800 Ankara, Turkey.

ACS Sensors
|January 17, 2018
PubMed
Summary

Early detection of Pseudomonas aeruginosa infections is crucial. This study demonstrates a novel optical biosensor for detecting Exotoxin A, a key virulence factor, in artificial sputum, achieving nanomolar sensitivity for improved Cystic Fibrosis diagnostics.

Keywords:
biological sensorcystic fibrosislabel-free detectionmicrotoroidoptical resonatorsurface modificationwhispering gallery-mode

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