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Updated: Feb 15, 2026

Electroporation of Craniofacial Mesenchyme
Published on: November 28, 2011
Severe Craniofacial Involvement due to Amniotic Band Sequence
Luis Eduardo Becerra-Solano1,2, Gema Castañeda-Cisneros3, Jorge Roman Corona-Rivera4
1a Instituto Mexicano del Seguro Social, Medical Research Unit , Gaudalajara , Mexico.
Background:
Disruptive amniotic band sequence (DABS) is a sporadic, non-familial disorder with unclear etiology. Diagnosis is based on clinical features because there is currently no reliable laboratory diagnostic tests.
Objective:
We describe six cases of DABS with severe craniofacial deformations, three with and three without classical constrictive limb deformation.
Results:
The craniofacial deformities were delimited by peripheral sharply demarcated scarring.
Conclusion:
When a sharply demarcated linear disruptive craniofacial lesion is observed, DABS should be considered despite the absence of constrictive limb scarring.
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